![]() A background analysisĪrticleTitleQuantitative investigation of X-ray diffraction by “amorphous” polymers and some other noncrystalline substances Physical Characterization of Pharmaceutical SciencesĪrticleTitleQuantitative X-ray investigation on the crystallinity of cellulose fibers. Occurrence Handle10.1016/0378-5173(94)90188-0ĪrticleTitleQuantitative crystallinity determinations for beta-lactam antibiotics by solution calorimetry: correlations with stability Occurrence Handle10.1016/0378-5173(94)90219-4ĪrticleTitleAssessment of the degree of disorder in crystalline solids by isothermal microcalorimetry Draft guidanceĪrticleTitlePharmaceutical solids: a strategic approach to regulatory considerationsĪrticleTitleThe quantitative analysis of crystallinity using FT-Raman spectroscopyĪrticleTitleAssessment of disorder in crystalline solids Department of Health and Human Services, Food and Drug AdministrationĪrticleTitleProcess analytical technology-a framework for innovative pharmaceutical manufacturing and quality assurance. InstitutionalAuthorNameInternational Conference on Harmonisation (ICH)ĪrticleTitleDraft guidance on Q6A specifications: test procedures and acceptance criteria for new drug substances and new drug products: chemical substances The first evidence of crystallization can serve as an indicator of the potential physical instability of the product.ĪrticleTitleEffect of formulation additives on the dissolution behavior of tetracycline antibioticsĪrticleTitleStability and several physical properties of amorphous and crystalline form of indomethacinĪrticleTitleSome pharmaceutical properties of novobiocinĪrticleTitleCryoprotective effect of saccharides on denaturation of catalase by freeze-dryingĪrticleTitleEffect of mannitol crystallinity on the stabilization of enzymes during freeze-dryingĪrticleTitleDecreased protein-stabilizing effects of cryoprotectants due to crystallizationĪrticleTitleCrystallization of indomethacin from the amorphous state below and above its glass transition temperature High-intensity XRD can discern subtle changes in the lattice order of materials. The estimated limit of detection of crystalline sucrose in an amorphous matrix was 0.2% w/w, a considerable improvement over the reported value of ∼1% w/w with a conventional XRD. The in situ crystallization approach circumvented the problem of inhomogeneity in mixing-a potentially serious issue at extreme mixture compositions. The gradual crystallization of sucrose is analogous to a series of physical mixtures with increasing content of the crystalline component. The synchrotron XRD technique allowed powder diffraction patterns to be recorded with a time resolution of 40 ms. ![]() An algorithm was developed for separation of the crystalline and amorphous intensities from the total diffraction pattern. The crystallization of amorphous sucrose was monitored in situ, isothermally at several temperatures in the range of 90 to 160☌. Methodsĭiffraction data were acquired at the European Synchrotron Radiation Facility (France) using a 2-D charge-coupled device detector. The aim of this study was to develop a highly sensitive powder X-ray diffraction (XRD) technique for quantification of crystallinity in substantially amorphous pharmaceuticals, utilizing synchrotron radiation and a 2-D area detector.
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A library of sample exercises provides an easy starting point for creating questions, and you can also create questions from scratch or edit questions from your course's online test bank. ![]() The MyLab Custom Question Builder (CQB) within MyLab Math lets you create static and algorithmic online exercises for a wide variety of mathematical and statistical topics. If you've spent time customizing your MyLab Statistics course and want to use the same course next semester, you can copy your existing course, preserve all your customizations, and share with other instructors. MyLab Statistics lets you manage multiple class sections, and other instructors can copy your settings so a standardized syllabus can be maintained across your department. Because all students have access by day one, faculty can start teaching and students can start learning. ![]() Offering course content through the Pearson Inclusive Access model can help students achieve more by providing affordable, high-quality digital course materials on or before the first day of class. Imagine the impact of first-day access on your course Having trouble watching the video? View the transcript Then, you can adjust your teaching accordingly, and even facilitate peer-to-peer learning, helping students stay motivated and engaged. You can monitor responses with real-time analytics and find out what your students do - and don’t - understand. Your students respond using their own smartphones, tablets, or laptops. You pose a variety of questions that help students recall ideas, apply concepts, and develop critical-thinking skills. 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Download data sets from the text and MyLab Statistics exercises directly into Excel ® Excel Projects let instructors seamlessly integrate Excel into their courses without having to manually grade spreadsheets. ![]() See a partial list of Applets and try them yourself.įor those using other statistical software programs, MyLab Statistics makes learning and using a variety of software programs as seamless and intuitive as possible. These applets cover a series of experiments and topics, from simple coin-flips to hypothesis testing, bootstrapping, and randomization. StatCrunch Applets provide a variety of simulations that can be used for in-class instruction, at-home exploration, or assessment. StatCrunch is integrated directly into MyLab Statistics or it can be purchased separately. The vibrant online community offers tens of thousands of shared data sets for students and instructors to analyze, in addition to all of the data sets in the text or online homework. StatCrunch ® is powerful, web-based statistical software that allows users to collect, crunch, and communicate with data. Encourage data analysis using integrated statistical software StatCrunch Always secure cargo using the floor-mounted tie-downs. Unsecured cargo can become hazardous in a collision. The Online Price excludes taxes and/or fees resulting from the sale of the vehicle, including, but not limited to destination charges, labour, title, license and installation charges. The actual purchase price of the vehicle is subject to change by the dealer and may vary based on location of the dealer and customer, inventory levels, vehicle features and available discounts and rebates. Refer to the Government of Canada's EnerGuide Fuel Consumption Guide or visit .ca for more information. The actual fuel consumption of these vehicles may vary. 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Make sure that you’re logged out of your user account and are currently at the Unix login screen. While BSD operating systems generally come with su, they seldom if ever come with the actual sudo command. Then, add your user to the sudo group using: Method 2: Fixing sudo command not found errors on FreeBSD and Other Unices. sudo: command not found How to Fix Error in Linux Sudo is a program that let users run programs with the security privileges of another user. As the root user, you can install the sudo package with the privileges this account possesses, so it’s not subject to the Linux “sudo command not found” error. How to Fix “sudo: command not found” on LinuxĪs your user cannot assume the privileges of the root user without already having sudo installed, you need to log out of your user account and log in as root. Demos are usually not time-limited (like Trial software) but the functionality is limited. 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Movavi Video Suite is a comprehensive video making program that helps you create professional-looking movies and slideshows on your home computer – even if you have no experience! ![]() Create awesome films with Movavi Video Suite. It is common in fandom to find widespread use of slang terms about shipping as a whole, as well as terms specific to individual fandoms.Ī - B - C - D - E - F - G - H - I - J - K - L - M - N - O - P - Q - R - S - T - U - V - W - X - Y - Z A list of terms with definitions used in shipping and associated fandoms. Alternate Universe - Often shortened to AU, Alternate Universe is a concept, typically in fanfictions where characters are imagined to be in different scenarios. showing only Science & Medicine definitions ( show all 9 definitions) Note: We have 3 other definitions for OTX in our Acronym Attic.Anti - A person who hates a ship to the point that part of the hatred is their obsession.Angst - A genre of fanfiction typically dedicated to being sad, angry, or just associated with negative feelings.įor instance, the characters in a medieval fantasy might be put in a modern universe (Modern AU). If you care about construction of either, then a rudimentary explanation is another matter. Dots are never on a screen and pixels are never on paper. A pixel is the smallest possible spot of light on a screen. Brotp - The term used when describing you ship a pairing platonically, or as friends.Buddyslash - The term for slash between characters who are friends, or more often, partners in canon.Bisexual triangle - a love triangle, one of the corners of which represents a canonical or potential homosexual attraction.Biromantic - Romantically attracted to people of either gender.Aromantic - Not romantically attracted to anyone.Some will get to the point where they threaten content creators. A dot is the smallest possible spot of ink on paper. Acronym /Abbreviation/Slang OTX means Online Testing Exchange. Used to refer to a pairing or another aspect of the series that is considered to be true to the story-line. OTX stand for Hop on to get the meaning of OTX. Crack Ship - A pairing that is considered to be way out there or impossible.Character - A character is a fictional invention who does not exist in real life.Cargo Ship - Ships between a person and an inanimate object. For example, you might say a chair has a wonky leg. ![]() You can use it to refer to a person or an object. Wonky is another word for shaky or unstable. Endgame - Ships that are canon at the end of the series.Drabble - A fic of 100 words, has come to usually denote a short fic of 100, 200 or 500 words or so.Crossover Ship - A paring between characters from different medias who have never interacted.Usually between characters who have never met each other or barely interacted. Watering hole this is one of the many British slang words for a pub. The importance of getting feedback on your current finances in retirement planning.A few of the levels of care offered here are Dual-Diagnosis, Inpatient, Outpatient. Hill Crest Behavioral Health Services is a licensed and accredited private rehab located in Birmingham, Alabama specializing in Dual Diagnosis (Co-Occuring Disorders), Mental Health, and Addiction Treatment. We can assist you on your journey to financial freedom: Learn more from this summarized breakdown. Listener question : Should I defer my Social Security? (7:00).Why and when the premise of the 4% rule fell apart.What is the 4% rule in retirement planning and is it still relevant? (0:46).Here is some of what we’ll discuss in today’s show: Freedom Financial Group Financial Advising Services in Birmingham, AL 35242 The Retire with Freedom Process Discover our five-step Retire with Freedom Process to building a confident retirement plan. Join us as we discuss why professional feedback and having a comprehensive financial plan is so critical and how fuzzy math in retirement planning can be a real problem. 43 through the Alabama night, through Grove Hill and on to Thomasville. After this, Toni and Tad will answer a recent listener question and share some things you need to be thinking about when it comes to Social Security. We’ll also discuss why it is so important to be professionally guided through financial decisions during the retirement planning process and share a story of some clients who were not adequately guided on withdrawal strategies before working with Freedom Financial Group. ![]() Does this rule really work? We’ll shed light on how this rule has come under question in recent years due to market conditions and share why this may not be a reliable strategy. In this episode, we’re going to discuss the widely known 4% rule in the financial industry, which suggests that retirees can safely withdraw 4% from their portfolio annually, adjusted for inflation, without running out of money. ![]() If you noticed that the Windows 10’s On-Screen Keyboard stopped working after a recent OS update, you should uninstall the update and roll back to the previous build. If the service status reads Stopped, tap the Start button, click Apply, and tap OK to save the changes. If the status reads Running, your On-Screen Keyboard should work fine. In addition to changing the startup type, you should also check the Service status of ‘Touch Keyboard and Handwriting Panel Service’. Now, try opening your PC’s On-Screen Keyboard and check if it works. Step 5: Finally, tap Apply and click OK to save the changes. ![]() Step 4: Tap the Startup type drop-down button and select Automatic. Step 3: Locate ‘Touch Keyboard and Handwriting Panel Service’ and double-click on it. Step 2: Enter service.msc into the Open dialog box and tap OK. Step 1: Launch the Windows Run box using the ‘Windows key + R’ keyboard shortcut. Reconfiguring the Touch Keyboard service (via the ‘Windows Management Console’) to start automatically could help to fix the On-Screen Keyboard not working issue. Also, you might encounter issues using the On-Screen Keyboard if the service is configured to startup manually. The Windows 10 On-Screen Keyboard is powered by the ‘Touch Keyboard and Handwriting Panel Service.’ If this service is disabled, your computer’s On-Screen Keyboard might not work. If this doesn’t work, proceed to the next troubleshooting fix. This will close the Create Shortcut window and you should now see the shortcut on your desktop.ĭouble-click the newly-created shortcut to launch the On-Screen Keyboard. Step 4: Enter a preferred name for the shortcut and tap Finish to conclude the shortcut creation process. Step 3: Type the directory below into the provided box and tap Next. Step 1: Right-click on a blank space on your PC’s desktop and select New on the context menu. This is another easy way to open the On-Screen Keyboard if it refuses to work/launch via conventional methods. This should immediately launch the On-Screen Keyboard on your PC screen. Simply open the Windows Run console using the ‘Windows logo key + R’ keyboard shortcut, type the command line below into the Open dialog box, and hit Enter on your keyboard. If your computer’s On-Screen Keyboard still isn’t coming up when you enable it either via keyboard shortcut or from the Settings menu, you can try force-enabling it using the Windows Run box. Step 3: Scroll to the Touch keyboard section and toggle on the ‘Show the touch keyboard when not in tablet mode and there’s no keyboard attached’ option. Step 2: Select Typing on the right-hand menu. Step 1: Launch the Windows Settings menu and select Devices. This will allow the On-Screen Keyboard to be accessible at all times. If your computer’s On-Screen Keyboard doesn’t come when Tablet mode isn’t active or when there’s no keyboard attached, follow the steps below to modify the Windows 10 Touch keyboard settings. Quick Tip: Press the Windows logo key + Ctrl + O keyboard shortcut to quickly launch the On-Screen keyboard on your Windows 10 computer. Whatever the case, refer to the tried and tested solutions in this guide to get your PC’s On-Screen Keyboard working again. However, there are some rare occasions where the virtual keyboard doesn’t work with just a particular app. ![]() When the On-Screen Keyboard fails to work, the issue is usually system-wide. But then, what happens when the On-Screen Keyboard fails to work when you need it? And how do you fix it? Dubbed the On-Screen Keyboard, you’d find this really handy if you use a PC/laptop with a touchscreen, or if your PC’s physical keyboard is faulty. The Windows operating system hands users the option of a secondary keyboard that can be used on the PC’s display. The response times vary, with some claims of seven days, and others up to eight weeks. All testing companies include the return shipping in their kits' pricing. You don't create an account with DNA My Dog, Instead, you simply register a kit to your name and email, and the company sends you a message with the results attached. If you send in a kit without registering it, you're probably not going to get the data. This can come in handy for trips to the vet. On the site, you can access all the final data, which you can then print out and save. Two of the services, Embark and Wisdom Panel, have you set up accounts on their websites, which can be used to register as many DNA kits as you like. The rest are essentially cotton swabs that you let dry out, then send back. The process doesn't differ much from service to service, though Embark seems a little more high-tech with its cotton sponge inserted into a stabilizing fluid for transport. It's preferable to do it without a lot of kibble residue, or dogs biting the swab. Do this a couple of hours after they eat the goal is to swab up as much DNA-laden saliva as possible for the labs to work with. After you register the kit, take a swab or two of the inside of the cheek pouch of your doggie. How Dog DNA Kits WorkĪll the kits we tried have the same basics. DNA My Dog conversely offers genetic screening tests, around 100, separately for $139.99. Embark and Wisdom Panel each sell a less expensive $99 version that only checks breed information and a minimal number of health problems. The expensive ones test for around 210 genetic issues. That said, we'd still argue it's the strongest reason to use a dog DNA test. "Probably a lot of what they screen for is very rare." Not, for instance, diabetes, which is acquired," she said, and listed off some other maladies. That said, she questions how prevalent the genetic problems tested by these kits are in the real world. She said that what she likes about the tests is that "there are things you can rule out, like dogs with neurological issues, say if they have a negative for degenerative myelopathy, that gives you very specific info. We spoke at length about DNA tests with a veterinarian, Dr. One company (that no longer sells a dog DNA test) claimed that its dog DNA results were used in a court case to show that a dog that was going to be euthanized for the "crime" of being a pit bull didn't, in fact, have any pittie in him.Īs mentioned earlier, the most important aspect of dog DNA testing is the genetic mutation/health checks that ensure your dog doesn't have potential issues. ![]() You could, however, use a DNA test to prove your dog's makeup does, or doesn't, include a breed. (Instead, you can opt for AKC Purebred Alternative Listing registration to get your hound into AKC run events, but that doesn't require a DNA test.) ![]() You can't suddenly prove your dog is purebred and petition the American Kennel Club (AKC) to let you register. Well, except for users of Embark, a service that's added a "Relatives" tab to its results that shows other dogs in the database with shared DNA. You're not going to find your dog's long-lost relatives. We can't stress enough that this is mostly meaningless. ![]() Why Bother Testing Your Dog's DNA?įor most people, the main reason to test is to be able to point at your dog and say, "Oh, she's a mix of this breed and that breed." It can serve as a confirmation that your expensive dog is indeed the purebred (or designer hybrid) that you paid for. The list includes DNA My Dog, Embark Dog DNA Test (Breed + Health Kit), and Wisdom Panel Premium. We looked at three dog DNA test services to see how they worked, evaluating them for their ease of use, presentation of data, and ability to match even their own test results with consistency. DNA tests can rule that out-or expose a disease before it's a problem. Your dog could be a carrier of these illnesses, or be at risk of developing the full-blown disorder. DNA tests also check your companion animal for a variety of gene-specific diseases or disorders-in other words, genetic mutations. There's another goal, though, that is discussed less, yet is arguably more important. |
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